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A middle-aged man with a troubled liver: Combination therapy in advanced (BCLC Stage C) hepatocellular carcinoma

Zamri Zuhdi, Azlanuddin Azman, Affirul Chairil Ariffin, Razman Jarmin, Hairol Azrin Othman.

Abstract
Advanced hepatocellular carcinoma carries a bad prognosis with a survival of only few months. Barcelona Clinic Liver Cancer (BCLC)
Guidelines recommended sorafenib monotherapy as the treatment modality for advanced BCLC Stage C disease, citing a two-month increase in survival rates. Here, we highlight a case with advanced HCC (BCLC Stage C) treated with combination therapy of liver resection and Sorafenib therapy. The patient’s current survival rate was beyond 10 months. We also discuss the current evidence on liver resection with Sorafenib therapy in hepatocellular carcinoma. The description of the case may benefit in future diagnosis and treatment.

Key words: Hepatocellular carcinoma, sorafenib, hepatectomy

 

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How to Cite this Article
Pubmed Style

Zuhdi Z, Azman A, Ariffin AC, Jarmin R, Othman HA. A middle-aged man with a troubled liver: Combination therapy in advanced (BCLC Stage C) hepatocellular carcinoma. doi:10.5455/aces.20170503080643


Web Style

Zuhdi Z, Azman A, Ariffin AC, Jarmin R, Othman HA. A middle-aged man with a troubled liver: Combination therapy in advanced (BCLC Stage C) hepatocellular carcinoma. www.scopemed.org/?mno=243853 [Access: November 20, 2017]. doi:10.5455/aces.20170503080643


AMA (American Medical Association) Style

Zuhdi Z, Azman A, Ariffin AC, Jarmin R, Othman HA. A middle-aged man with a troubled liver: Combination therapy in advanced (BCLC Stage C) hepatocellular carcinoma. doi:10.5455/aces.20170503080643


Vancouver/ICMJE Style

Zuhdi Z, Azman A, Ariffin AC, Jarmin R, Othman HA. A middle-aged man with a troubled liver: Combination therapy in advanced (BCLC Stage C) hepatocellular carcinoma. doi:10.5455/aces.20170503080643


Harvard Style

Zuhdi, Z., Azman, A., Ariffin, A. C., Jarmin, R. & Othman, H. A. (2018) A middle-aged man with a troubled liver: Combination therapy in advanced (BCLC Stage C) hepatocellular carcinoma. doi:10.5455/aces.20170503080643


Turabian Style

Zuhdi, Zamri, Azlanuddin Azman, Affirul Chairil Ariffin, Razman Jarmin, and Hairol Azrin Othman. 2018. A middle-aged man with a troubled liver: Combination therapy in advanced (BCLC Stage C) hepatocellular carcinoma. doi:10.5455/aces.20170503080643


Chicago Style

Zuhdi, Zamri, Azlanuddin Azman, Affirul Chairil Ariffin, Razman Jarmin, and Hairol Azrin Othman. “A middle-aged man with a troubled liver: Combination therapy in advanced (BCLC Stage C) hepatocellular carcinoma.” doi:10.5455/aces.20170503080643


MLA (The Modern Language Association) Style

Zuhdi, Zamri, Azlanuddin Azman, Affirul Chairil Ariffin, Razman Jarmin, and Hairol Azrin Othman. “A middle-aged man with a troubled liver: Combination therapy in advanced (BCLC Stage C) hepatocellular carcinoma.” doi:10.5455/aces.20170503080643


APA (American Psychological Association) Style

Zuhdi, Z., Azman, A., Ariffin, A. C., Jarmin, R. & Othman, H. A. (2018) A middle-aged man with a troubled liver: Combination therapy in advanced (BCLC Stage C) hepatocellular carcinoma. doi:10.5455/aces.20170503080643